The big question that has circulated around the hosta world since the beginning of tissue culture (TC) is, “Are tissue cultured hostas as good as those divided from a plant growing in the ground?” The answer is a resounding, YES! Just like taking a knife and cutting a part of a hosta crown off to make a division, TC plants are exactly the same as the mother plant.
I think some of the confusion comes from a couple of factors. First, in their effort to make a quicker return on their investment, some nurseries sell tiny, little TC plants in two inch pots. Of course, it may take a year or two for these to grow to the size of a single division taken directly from a mature mother plant. But, they will eventually catch up.